Violet Therapeutics are Targeting EphB3 for Neurodegenerative Diseases including Alzheimer's
Violet Therapeutics is a platform biotech company that identified EphB3 as a cell receptor involved in neuroinflammation. This article discusses their development of covalent small molecule inhibitors of EphB3.
Part 3: Patent Busting A Literature-based Approach
Part 3 of the patent busting Literature-based Approach series focuses on
identifying GAPS in a patent focused on
STING antagonists and discusses how to differentiate to design novel chemical matter.
Vinyl sulfonimidamides as a new cysteine reactive electrophile
Sanofi completes buyout of Vigil Neurosciences for a small molecule TREM2 agonist program
ChemUI Seek: Download this cool chemical structure search application
Part 2: The case for CD47-SIRPα small molecule inhibition
The case for CD47-SIRPα small molecule inhibition
The other day I was perusing Arch Venture’s company portfolio and landed on...
Orthosteric versus allosteric SARM1 inhibitors
APOE4 increases inflammation related pathways
Patent Busting A Literature-based Approach
Part 2: Patent Busting A Literature-based Approach
My First Article! Allow me to introduce myself
Welcome to my first ever blog post! I know the name ChemJam might seem like a terrible choice to many people, but the domain name was supremely cheap, and I currently don’t have a consistent income right now (Hire me!). So, you will just have to deal with it...